Product Description
Volume 1 discusses the general characters of bacteria, the medical aspects of bacterial and bacteriophage emphasizing aspects of medical relevance in the subject, bacteria in the environment, bacteriology of foods other than milk and milk products and bacteria associated with the animal body. ... Read more

Product Description
Microbes have co-evolved over time with other organisms to the extent that some are so acquainted with host cell biology that they subvert key cellular processes with unrivalled precision. This volume reviews this exciting new discipline, reflecting the recent explosion of knowledge as well as broader insights into fundamental cellular processes.C. David O'Connor and David Smith cover the salient aspects by using a range of model systems. ... Read more

Product Description
Univ. College, London, U.K. Cogently written and supplemented with numerous line drawings, the book also includes self-test exercises, appendices, glossary, and reading lists. ... Read more

Product Description
Novel microorganisms which are capable of growth at environmental extremes have long been a rich resource for fundamental research. Of more recent interest is the recognition and exploitation of their genetic and biotechnological potential. This volume provides a much-needed summary of fundamental and applied research in the field. ... Read more

Product Description
The true extent of prokaryote diversity, encompassing the spectrum of variability among bacteria, remains unknown. Current research efforts focus on understanding why prokaryote diversification occurs, its underlying mechanisms, and its likely impact. The dynamic nature of the prokaryotic world, and continuing advances in the technological tools available make this an important area and hence this book will appeal to a wide variety of microbiologists. Its coverage ranges from studies of prokaryotes in specialized environmental niches to broad examinations of prokaryote evolution and diversity, and the mechanisms underlying them. Topics include: bacteria of the gastrointestinal tract, unculturable organisms in the mouth and in the soil, organisms from extreme environments, the diversity of archaea and their phages, comparative genomics and the emergence of pathogens, the spread of genomic islands between clinical and environmental organisms, minimal genomes needed for life, horizontal gene transfer, phenotypic innovation, and patterns and extent of biodiversity. ... Read more

Product Description
This book evaluates the increasing wealth of knowledge that has accumulated concerning the regulation of synthesis and assembly of structural components of the bacterial cell. It is now possible in many cases to trace the exact sequence of events triggered by a change in the physical or chemical environment of a bacterial cell, for instance, signaling, gene expression, transport of the gene product to its correct location, and assembly into a functional structure. The scope of this volume is broad, ranging from the organization of the nuclear material itself to the sequence of events leading to differentiation and development; from the synthesis of intracellular storage material to the assembly of specialized photosynthetic membranes, periplasmic electron transfer chains, and heat-resistant spores. ... Read more

Product Description
This volume brings together authoritative articles summarizing the current state of knowledge of the genetic organization of bacterial populations. Contributions include the evolution of E. coli populations, the roles of gene transfer and recombination, the distribution and evolution of plasmids and antibiotic resistance, population genetics of phase-variable systems, population dynamics and epidemiology of bacterial pathogens, and plasmid transfer in the natural environment. Similarities and differences with the population genetics of higher organisms are emphasized throughout, and the impact of bacterial studies on current evolutionary theories highlighted. The consequences of population structure in clinical practice, environmental situations and commercial exploitation of bacteria are also considered in this professional level book. ... Read more

Product Description
LABORATORY MANUAL IN GENERAL MICROBIOLOGY PREPARED BY THE LABORATORY OF BACTERIOLOGY AND HYGIENE MICHIGAN AGRICULTURAL COLLEGE - -1916 -- PREFATORY NOTE LABORATORY instruction in bacteriology at the Michigan Agricultural College developed under the direction of Dr. C. E. Marshall. This laboratory guide represents the accumulated efforts of instructors working for a period in excess of a decade. To Assistant Professor L. Zae Northrup is due the credit for collecting and arranging the material presented as well as for preparing de novo many of the experiments and much of the supplementary matter. She has been assisted by Mr. W. L. Kulp. Dr. E. T. Hallman and Dr. L. R. immelberer have taken the responsibility for arranging the exercises relating to immunity, serum therapy and pathologic bacteriology. Great praise is due Dr. F. H. H. Van Suchtelen for introducing many new features into the laboratory work during the academic year 1912-13, and also Dr. Otto Rahn for his several years of admirable effort immediately preceding. Others whose influence has been felt in creating this guide and to whom credit is due are Professors W. G. Sackett, S. F. Edwards, L. D. Bushnell, C. W. Brown and W. H. Wright. While some claim to originality may be made for- this laboratory guide, it is to be expected that much of the material herein has been presented in various other manuals and perhaps in better form in many instances. The greatest effort has been made to make this a laboratory guide to General Microbiology, leaving the particular fields of dairy, soil, water, medical and other phases of bacteriology to special guides already in print or at present projected. The presentation of this manual to the public i in . no - .. way anintimation that the special fields have not been admirably dealt with by others. The subject matter given under Part I of this manual is primarily for the purpose of giving a working knowledge of laboratory methods used in the study of microorganisms. Molds, yeasts and bacteria are taken up in the order of their comparative sizes.and studied as to their identification by morphological and cultural methods. It is presupposed that the student has a knowledge of these microorganisms acquired from preceding lectures in microbiology. Part I1 consists of exercises demonstrating the various physiological activities of microorganisms. Part I11 deals with applied microbiology. After the student has familiarized himself with the ordinary tools and technic, etc., as dealt with in Parts I and 11, it is not neces- - sary that he be burdened with minute, detailed instructions. We have had this in mind in preparing Part 111. No attempt has been made to compile an exhaustive list of exercises the aim has been only to cover a wide range of activities under each different subject. In many cases, exercises have been taken directly, with few or no modifications, from laboratory manuals already in print. Credit has not been given directly the list of references, however, includes all books from which material has been taken. The purpose of this laboratory manual is to make the student more independent. Practically all directions for work to be done are contained in-it for this reason the work as assigned from day to day should be read-over carefully before beginning an exercise and then followed step by step. Any desirable changes in directions may be indicated by the instructor. WARD GILTNER, Head of Department, EAST LANSING, MICH. Sept. 1, 1915. CONTENTS PART I GENERAL MORPHOLOGICAL AND CULTURAL METHODS PAGE .............................. ............................................... .......... ............................................ .............................. Exercise 1 . Cleaning Glassware 1 Sterilization 5 Exercise 2 ... ... Read more

Product Description
This volume describes the regulatory mechanisms which operate at the level of gene expression. The authors primarily discuss bacterial systems but some consideration is also given to lower eukaryotes. The early chapters of the book deal with regulation of gene expression in the context of cellular physiology. Subsequent chapters deal with the major new developments in our understanding of the molecular basis of the control of gene expression, namely: promoter/operator structure; DNA-protein interaction; control of mRNA turnover; positive regulation of gene expression; antisense RNA; DNA supercoiling; and transcription termination. The final two chapters consider specific problems in gene expression in Streptomycetes and in Dictyostelium. ... Read more

Product Description
This is an authoritative and timely account of the two major weapons in the fight against virus disease: immunization and chemotherapy. The first half of the volume covers the development and the use of vaccines as part of an immunization program.The latter half examines the role of chemotherapy in the control and therapy of diseases such as influenza, hepatitis and AIDS. This book will be useful to clinical virologists, immunologists, epidemiologists and research scientists in chemotherapy, drug development and immunization. ... Read more